Product overview

Name β-Amyloid Peptide (25-35) (human)
Description β-Amyloid (25-35) protein fragment
Biological description

β-Amyloid (25-35) is a synthetic peptide fragment of the amyloid beta protein. It shows neurotoxic activity.

Purity >95%
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Solubility & Handling

Storage instructions -20°C
Solubility overview Freely soluble in H2O.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

Chemical name GSNKGAIIGLM
Molecular Weight 1060.27
Chemical structure Amyloid beta 25-35 TFA [131602-53-4] Chemical Structure
Molecular Formula C45H81N13O14S
Sequence (one letter) GSNKGAIIGLM
Sequence (three letter) H-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-OH
Modifications N/A
CAS Number 131602-53-4
PubChem identifier 10843733
SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CO)NC(=O)CN
InChiKey WIHBNMPFWRHGDF-SLVFWPMISA-N
MDL number MFCD00133076
Appearance Lyophilized White solid
Protein length 11

References for β-Amyloid Peptide (25-35) (human)

References are publications that support the biological activity of the product
  • Effect of Beta-amyloid (25-35) on mitochondrial function and expression of mitochondrial permeability transition pore proteins in rat hippocampal neurons

    Ren R et al (2011) J Cell Biochem 112(5) : 1450-7
  • Abeta(31-35) and Abeta(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: Role of the redox state of methionine-35

    Clementi ME et al (2005) FEBS Lett 579(13) : 2913-8
  • Amyloid-beta(25-35)-induced memory impairments correlate with cell loss in rat hippocampus

    Stepanichev MY et al (2004) Physiol Behav 80(5) : 647-55