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Thioflavin T (ThT)

(HB7143)
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Product overview

Name Thioflavin T (ThT)
Alternative names Thioflavin T
Purity >95%
Description

Cell-permeable fluorescent amyloid stain

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description Cell-permeable fluorescent amyloid stain used to detect amyloid fibrils and used to study amyloid fibril structure and the mechanism by which they form.

Solubility & Handling

Storage instructions -20°C
Solubility overview

Soluble in water (10 mM), and in DMSO (5 mM)

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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More Info

Dilution

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More Info

Chemical Data

Purity >95%
Chemical name 2-[4-(Dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chloride
Molecular Weight 318.9
Chemical structure Chemical Structure
Molecular Formula C17H19ClN2S
CAS Number 2390-54-7
PubChem identifier 16853
SMILES CC1=CC2=C(C=C1)[N+](=C(S2)C3=CC=C(C=C3)N(C)C)C.[Cl-]
InChi InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChiKey JADVWWSKYZXRGX-UHFFFAOYSA-M

References for Thioflavin T (ThT)

References are publications that support the biological activity of the product

  • Thioflavin T fluoresces as excimer in highly concentrated aqueous solutions and as monomer being incorporated in amyloid fibrils.

    Sulatskaya AI et al (2017) Scientific reports 7 : 2146
    Read more (PubMedID: 28526838)

  • Mechanism of thioflavin T binding to amyloid fibrils.

    Khurana R et al (2005) Journal of structural biology 151 : 229-38
    Read more (PubMedID: 16125973)

  • The binding of thioflavin-T to amyloid fibrils: localisation and implications.

    Krebs MR et al (2005) Journal of structural biology 149 : 30-7
    Read more (PubMedID: 15629655)

3 Item(s)

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Grouped product items
Order: HB7143
Pack PriceQty
100mg
$50
500mg
$80

Cell-permeable fluorescent amyloid stain

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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