Product overview

Name Temozolomide
Purity >99%
Description DNA-methylating antitumor agent
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Biological Data

Biological description DNA-methylating antitumor agent. Shows anti-tumor activity against leukemias, lymphomas and solid tumors. Also induces autophagy in malignant glioma cells.

Solubility & Handling

Solubility overview Soluble in DMSO (5 mg/ml)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide
Molecular Weight 194.15
Chemical structure  Chemical Structure
Molecular Formula C6H6N6O2
CAS Number 85622-93-1

References for Temozolomide

References are publications that support the biological activity of the product
  • Matteucinol combined with temozolomide inhibits glioblastoma proliferation, invasion, and progression: an in vitro, in silico, and in vivo study.

    Netto JB et al (2022) Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 55 : e12076
  • Considering the Experimental use of Temozolomide in Glioblastoma Research.

    Herbener VJ et al (2020) Biomedicines 8 :
  • Temozolomide: mechanisms of action, repair and resistance.

    Zhang J et al (2012) Current molecular pharmacology 5 : 102-14

3 Item(s)