Product overview

Name Temozolomide
Purity >99%
Description DNA-methylating antitumor agent
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Biological Data

Biological description DNA-methylating antitumor agent. Shows anti-tumor activity against leukemias, lymphomas and solid tumors. Also induces autophagy in malignant glioma cells.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (5 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide
Molecular Weight 194.15
Chemical structure  Chemical Structure
Molecular Formula C6H6N6O2
CAS Number 85622-93-1

References for Temozolomide

References are publications that support the biological activity of the product
  • Matteucinol combined with temozolomide inhibits glioblastoma proliferation, invasion, and progression: an in vitro, in silico, and in vivo study.

    Netto JB et al (2022) Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 55 : e12076
  • Considering the Experimental use of Temozolomide in Glioblastoma Research.

    Herbener VJ et al (2020) Biomedicines 8 :
  • Temozolomide: mechanisms of action, repair and resistance.

    Zhang J et al (2012) Current molecular pharmacology 5 : 102-14

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