Recombinant rat CDNF protein

Technical documents: Datasheet

Product overview

Name Recombinant rat CDNF protein
Alternative names Recombinant Rat Cerebral Dopamine Neurotrophic Factor, Cerebral neurotrophic factor, ARMET-like protein 1, Arginine-rich protein mutated in early stage tumors-like 1, Conserved neurotrophic factor, Cdnf, Armetl1.
Purity >97%
Description Rat CDNF protein
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Biological Data

Application notes Enhances neurite outgrowth of E16-E18 rat embryonic cortical neurons when immobilized at 5-25 µg/mL on a nitrocellulose-coated microplate.

Solubility & Handling

Solubility overview To make a stock solution, reconstitute in sterile 18MΩcm water at a concentration > 100μg/ml, which can then be diluted to make a working solution
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use



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Chemical Data

Purity >97%
Source E. Coli.
Appearance White lyophilized powder (sterile filtered & freeze-dried)
Formulation Lyophilized from a 0.2μm filtered solution in PBS (pH 7.4)

References for Recombinant rat CDNF protein

References are publications that support the biological activity of the product
  • CDNF Protein Therapy in Parkinson's Disease

    Huttunen HJ et al (2019) Cell Transplant 28(4) : 349-366
  • Characterization of recombinant human brain-derived neurotrophic factor variants

    Sunasara KM et al (1999) Arch Biochem Biophys 372(2) : 248-60
  • Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector-mediated peptide drug delivery

    Pardridge WM et al (1994) Pharm Res 11(5) : 738-46

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