Fully biologically active when compared to standard. ED50 = <0.1ng/ml (determined by a cell proliferation assay using human TT medullary thyroid cancer cells), corresponding to a specific activity of > 1.0 x 10,000,000 IU/mg
Solubility & Handling
Solubility overview
To make a stock solution, reconstitute in sterile 18MΩcm water at a concentration > 100µg/ml, which can then be diluted to make a working solution
Handling
Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease
Akerud P et al (2002) Mol Cell Neurosci 21(2) : 205-22
