Recombinant mouse Midkine protein

(HB6469)
Technical documents: Datasheet

Product overview

Name Recombinant mouse Midkine protein
Alternative names Recombinant Mouse Midkine, NEGF-2, Neurite Growth-Promoting Factor 2, MK, Neurite outgrowth-promoting protein, Midgestation and kidney protein, Amphiregulin-associated protein, ARAP, Neurite outgrowth-promoting factor 2, FLJ27379, Midkine, MK1, NEGF2.
Purity >95%
Description Mouse Midkine recombinant protein
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Biological Data

Application notes Fully biologically active when compared to standard. Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml corresponding to a specific activity of 10,000-100,000IU/mg.

Solubility & Handling

Solubility overview To make a stock solution, reconstitute in sterile 18MΩcm water at a concentration > 100μg/ml, which can then be diluted to make a working solution
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • Freeze-thaw cycles should be prevented.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
UniProt ID P12025
Source E. Coli.
Structure image  Chemical Structure
Appearance White lyophilized powder (sterile filtered & freeze-dried)
Formulation Lyophilized from a 0.2μm filtered solution in PBS (pH 7.4)

References for Recombinant mouse Midkine protein

References are publications that support the biological activity of the product
  • Midkine: a promising molecule for drug development to treat diseases of the central nervous system

    Muramatsu T (2011) Curr Pharm Des 17(5) : 410-23
  • Astroglial neurotrophic and neurite-promoting factors

    Muller HW et al (1995) Pharmacol Ther 65(1) : 43101
  • Laminin is associated with the neurite outgrowth-promoting factors" found in conditioned media"

    Lander AD et al (1985) Proc Natl Acad Sci U S A 82(7) : 2183-7

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