Recombinant mouse CNTF protein

(HB8930)
Technical documents: Datasheet

Product overview

Name Recombinant mouse CNTF protein
Alternative names Recombinant Mouse Ciliary Neurotrophic Factor, HCNTF, CNTF, Ciliary Neurotrophic Factor.
Purity >97%
Description Mouse CNTF protein
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Biological Data

Application notes Fully biologically active when compared to standard. ED50 = <35ng/ml (determined by the dose-dependant stimulation of TF-1 cells), corresponding to a Specific Activity of 3.0x104 IU/mg.

Solubility & Handling

Solubility overview To make a stock solution, reconstitute in sterile 18MΩcm water at a concentration > 100μg/ml, which can then be diluted to make a working solution
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • Freeze-thaw cycles should be prevented.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >97%
UniProt ID P51642
Source E. Coli.
Structure image  Chemical Structure
Appearance White lyophilized powder (sterile filtered & freeze-dried)
Formulation Lyophilized from a 0.2μm filtered solution in PBS (pH 7.4)

References for Recombinant mouse CNTF protein

References are publications that support the biological activity of the product
  • Ciliary neurotrophic factor (CNTF): New facets of an old molecule for treating neurodegenerative and metabolic syndrome pathologies

    Pasquin S et al (2015) Cytokine Growth Factor Rev 26(5) : 507-15
  • Ciliary neurotrophic factor (CNTF) promotes skeletal muscle progenitor cell (MPC) viability via the phosphatidylinositol 3-kinase-Akt pathway

    Hiatt K et al (2014) J Tissue Eng Regen Med 8(12) : 963-8
  • The ciliary neurotrophic factor and its receptor, CNTFR alpha

    Sleeman MW et al (2000) Pharm Acta Helv 74(2-3) : 265-72

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