Recombinant mouse CNTF protein

(HB8930)
Technical documents: Datasheet

Product overview

Name Recombinant mouse CNTF protein
Alternative names Recombinant Mouse Ciliary Neurotrophic Factor, HCNTF, CNTF, Ciliary Neurotrophic Factor.
Purity >97%
Description Mouse CNTF protein
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Biological Data

Application notes Fully biologically active when compared to standard. ED50 = <35ng/ml (determined by the dose-dependant stimulation of TF-1 cells), corresponding to a Specific Activity of 3.0x104 IU/mg.

Solubility & Handling

Solubility overview To make a stock solution, reconstitute in sterile 18MΩcm water at a concentration > 100μg/ml, which can then be diluted to make a working solution
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >97%
Source E. Coli.
Appearance White lyophilized powder (sterile filtered & freeze-dried)
Formulation Lyophilized from a 0.2μm filtered solution in PBS (pH 7.4)

References for Recombinant mouse CNTF protein

References are publications that support the biological activity of the product
  • Ciliary neurotrophic factor (CNTF): New facets of an old molecule for treating neurodegenerative and metabolic syndrome pathologies

    Pasquin S et al (2015) Cytokine Growth Factor Rev 26(5) : 507-15
  • Ciliary neurotrophic factor (CNTF) promotes skeletal muscle progenitor cell (MPC) viability via the phosphatidylinositol 3-kinase-Akt pathway

    Hiatt K et al (2014) J Tissue Eng Regen Med 8(12) : 963-8
  • The ciliary neurotrophic factor and its receptor, CNTFR alpha

    Sleeman MW et al (2000) Pharm Acta Helv 74(2-3) : 265-72

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