Recombinant human Pleiotrophin protein

(HB7515)
Technical documents: CoA Datasheet

Product overview

Name Recombinant human Pleiotrophin protein
Biological description

Heparin-binding cytokine that signals diverse functions, including lineage-specific differentiation of glial progenitor cells, neurite outgrowth, and angiogenesis.

Alternative names Recombinant Human Pleiotrophin, PTN, Heparin Affin Regulatory Protein, HARP, Heparin-binding growth factor-8, HBGF-8, Osteoblast-Specific Factor-1, OSF-1, Heparin-binding growth-associated molecule, HB-GAM, HBNF-1 Heparin-binding brain mitogen, Heparin-binding neurite outgrowth-promoting factor 1, HBBM, NEGF1.
Purity >97%
Description Heparin-binding cytokine
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Solubility & Handling

Storage instructions -20°C
Solubility overview To make a stock solution, reconstitute the lyophilized Pleiotrophin in sterile 18MΩcm water at a concentration > 100μg/ml, which can then be diluted to make a working solution
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >97%
Molecular Weight 15.3
Source E. Coli.
Appearance White lyophilized powder (sterile filtered & freeze-dried)
Formulation Lyophilized from a 0.2μm filtered solution in PBS (pH 7.4)

References for Recombinant human Pleiotrophin protein

References are publications that support the biological activity of the product
  • Pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta as regulators of angiogenesis and cancer

    Papadimitriou E et al (2016) Biochim Biophys Acta 1866(2) : 252-265
  • Pleiotrophin, a multifunctional angiogenic factor: mechanisms and pathways in normal and pathological angiogenesis

    Perez-Pinera P et al (2008) Curr Opin Hematol 15(3) : 210-4
  • Pleiotrophin: a cytokine with diverse functions and a novel signaling pathway

    Deuel TF et al (2002) Arch Biochem Biophys 397(2) : 162-71

3 Item(s)