Recombinant human Pleiotrophin protein

(HB7515)
Technical documents: CoA Datasheet

Product overview

Name Recombinant human Pleiotrophin protein
Biological description

Heparin-binding cytokine that signals diverse functions, including lineage-specific differentiation of glial progenitor cells, neurite outgrowth, and angiogenesis.

Alternative names Recombinant Human Pleiotrophin, PTN, Heparin Affin Regulatory Protein, HARP, Heparin-binding growth factor-8, HBGF-8, Osteoblast-Specific Factor-1, OSF-1, Heparin-binding growth-associated molecule, HB-GAM, HBNF-1 Heparin-binding brain mitogen, Heparin-binding neurite outgrowth-promoting factor 1, HBBM, NEGF1.
Purity >97%
Description Heparin-binding cytokine
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Solubility & Handling

Storage instructions -20°C
Solubility overview To make a stock solution, reconstitute the lyophilized Pleiotrophin in sterile 18MΩcm water at a concentration > 100μg/ml, which can then be diluted to make a working solution
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >97%
UniProt ID P21246
Molecular Weight 15.3
Source E. Coli.
Appearance White lyophilized powder (sterile filtered & freeze-dried)
Formulation Lyophilized from a 0.2μm filtered solution in PBS (pH 7.4)

References for Recombinant human Pleiotrophin protein

References are publications that support the biological activity of the product
  • Pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta as regulators of angiogenesis and cancer

    Papadimitriou E et al (2016) Biochim Biophys Acta 1866(2) : 252-265
  • Pleiotrophin, a multifunctional angiogenic factor: mechanisms and pathways in normal and pathological angiogenesis

    Perez-Pinera P et al (2008) Curr Opin Hematol 15(3) : 210-4
  • Pleiotrophin: a cytokine with diverse functions and a novel signaling pathway

    Deuel TF et al (2002) Arch Biochem Biophys 397(2) : 162-71

3 Item(s)