Fully biologically active when compared to standard. ED50 = <10ng/ml (determined by a cell proliferation assay using human TT medullary thyroid cancer cells), corresponding to a specific activity of > 1.0 x 100,000 IU/mg
Solubility & Handling
Storage instructions
-20°C
Solubility overview
To make a stock solution, reconstitute in 4mM HCl at a concentration > 100μg/ml, which can then be diluted to make a working solution
Handling
Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease
Akerud P et al (2002) Mol Cell Neurosci 21(2) : 205-22
