Recombinant human PEDF/Serpin-F1 (HEK expressed) protein

(HB7366)
Technical documents: Datasheet

Product overview

Name Recombinant human PEDF/Serpin-F1 (HEK expressed) protein
Alternative names Recombinant Human Pigment Epithelium-Derived Factor, HEK, Pigment epithelium-derived factor, PEDF, Serpin-F1, SerpinF1, EPC-1, EPC1, PIG35.
Purity >95%
Description HEK expressed recombinant human PEDF/Serpin-F1 protein
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Solubility & Handling

Solubility overview To make a working stock solution, add deionized water to make a solution (0.5mg/mL) and allow the lyophilized material to dissolve. Filter the product using an appropriate sterile filter before using it in cell culture
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • Freeze-thaw cycles should be prevented.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
UniProt ID P36955
Source HEK 293.
Structure image  Chemical Structure
Appearance White lyophilized powder (filtered & freeze-dried)
Formulation Lyophilized from filtered (0.4μm) solution (0.5mg/ml) containing Tris (20mM) & NaCl pH 7.5 (20mM)

References for Recombinant human PEDF/Serpin-F1 (HEK expressed) protein

References are publications that support the biological activity of the product
  • PEDF and its roles in physiological and pathological conditions: implication in diabetic and hypoxia-induced angiogenic diseases

    He X et al (2015) Clin Sci (Lond) 128(11) : 805-23
  • Pigment epithelium-derived factor (PEDF) is one of the most abundant proteins secreted by human adipocytes and induces insulin resistance and inflammatory signaling in muscle and fat cells

    Famulla S et al (2011) Int J Obes (Lond) 35(6) : 762-72
  • PEDF: a multifaceted neurotrophic factor

    Tombran-Tink J et al (2003) Nat Rev Neurosci 4(8) : 628-36

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