Recombinant human Neurogenin-3 protein

(HB9047)
Technical documents: Datasheet

Product overview

Name Recombinant human Neurogenin-3 protein
Biological description

The Neurogenin-3 transcription factor is implicated in the control of dendrite morphology and synaptic plasticity of cultured hippocampal neurons.

Alternative names Recombinant Human Neurogenin 3, Neurogenin 3, Class A Basic Helix-Loop-Helix Protein 7, Protein Atonal Homolog 5, BHLHA7, Math4B, NGN3, Atoh5.
Purity >85%
Description Transcription factor that is involved in neurogenesis
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Solubility & Handling

Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

Purity >85%
Source E. Coli.
Appearance Clear solution (sterile filtered)
Formulation Solution (0.25mg/ml) containing Tris-HCl buffer (20mM, pH 8.0), 0.4M Urea and 10% glycerol

References for Recombinant human Neurogenin-3 protein

References are publications that support the biological activity of the product
  • Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate

    Gomez DL et al (2015) PLoS One 10(8) : e0133862
  • Neurogenin 3 cellular and subcellular localization in the developing and adult hippocampus

    Simon-Areces J et al (2010) J Comp Neurol 518(10) : 1814-24
  • Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types

    Schonhoff SE et al (2004) Dev Biol 270(2) : 443-54

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