Recombinant human Neurogenin-3 protein

(HB9047)
Technical documents: Datasheet

Product overview

Name Recombinant human Neurogenin-3 protein
Biological description

The Neurogenin-3 transcription factor is implicated in the control of dendrite morphology and synaptic plasticity of cultured hippocampal neurons.

Alternative names Recombinant Human Neurogenin 3, Neurogenin 3, Class A Basic Helix-Loop-Helix Protein 7, Protein Atonal Homolog 5, BHLHA7, Math4B, NGN3, Atoh5.
Purity >85%
Description Transcription factor that is involved in neurogenesis
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Solubility & Handling

Storage instructions

-20°C

Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >85%
Molecular Weight 25.1
Sequence (one letter) MGSSHHHHHH SSGLVPRGSH MTPQPSGAPT VQVTRETERS FPRASEDEVT CPTSAPPSPT RTRGNCAEAE EGGCRGAPRK LRARRGGRSR PKSELALSKQ RRSRRKKAND RERNRMHNLN SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSLYALE PPAPHCGELG SPGGSPGDWG SLYSPVSQAG SLSPAASLEE RPGLLGATSS ACLSPGSLAF SD
Source E. Coli.
Appearance Clear solution (sterile filtered)
Formulation Solution (0.25mg/ml) containing Tris-HCl buffer (20mM, pH 8.0), 0.4M Urea and 10% glycerol

References for Recombinant human Neurogenin-3 protein

References are publications that support the biological activity of the product
  • Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate

    Gomez DL et al (2015) PLoS One 10(8) : e0133862
  • Neurogenin 3 cellular and subcellular localization in the developing and adult hippocampus

    Simon-Areces J et al (2010) J Comp Neurol 518(10) : 1814-24
  • Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types

    Schonhoff SE et al (2004) Dev Biol 270(2) : 443-54

3 Item(s)