Recombinant human Myotrophin / MTPN protein

(HB9734)
Technical documents: Datasheet

Product overview

Name Recombinant human Myotrophin / MTPN protein
Biological description

Factor that stimulates protein synthesis and cardiomyocyte growth to commence cardiac hypertrophy by activating the NF-kappaB signaling cascade.

Alternative names Recombinant Human Myotrophin, Protein V-1, GCDP, Myotrophin, FLJ31098, FLJ99857.
Purity >90%
Description Factor that stimulates myocyte growth
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Solubility & Handling

Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

Purity >90%
Source E. Coli.
Appearance Colourless solution (sterile filtered)
Formulation Solution containing Tris-HCl (20mM, pH8) and 10% glycerol

References for Recombinant human Myotrophin / MTPN protein

References are publications that support the biological activity of the product
  • Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure

    Das B et al (2010) Cardiovasc Res 87(3) : 524-34
  • Cardiac overexpression of myotrophin triggers myocardial hypertrophy and heart failure in transgenic mice

    Sarkar S et al (2004) J Biol Chem 279(19) : 20422-34
  • Myotrophin in human cardiomyopathic heart

    Sil P et al (1993) Circ Res 73(1) : 98-108

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