Recombinant human Myotrophin / MTPN protein

(HB9734)
Technical documents: Datasheet

Product overview

Name Recombinant human Myotrophin / MTPN protein
Biological description

Factor that stimulates protein synthesis and cardiomyocyte growth to commence cardiac hypertrophy by activating the NF-kappaB signaling cascade.

Alternative names Recombinant Human Myotrophin, Protein V-1, GCDP, Myotrophin, FLJ31098, FLJ99857.
Purity >90%
Description Factor that stimulates myocyte growth
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Solubility & Handling

Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >90%
UniProt ID P58546
Source E. Coli.
Structure image  Chemical Structure
Appearance Colourless solution (sterile filtered)
Formulation Solution containing Tris-HCl (20mM, pH8) and 10% glycerol

References for Recombinant human Myotrophin / MTPN protein

References are publications that support the biological activity of the product
  • Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure

    Das B et al (2010) Cardiovasc Res 87(3) : 524-34
  • Cardiac overexpression of myotrophin triggers myocardial hypertrophy and heart failure in transgenic mice

    Sarkar S et al (2004) J Biol Chem 279(19) : 20422-34
  • Myotrophin in human cardiomyopathic heart

    Sil P et al (1993) Circ Res 73(1) : 98-108

3 Item(s)