Recombinant human MANF (His Tag) protein

(HB7200)
Technical documents: Datasheet

Product overview

Name Recombinant human MANF (His Tag) protein
Alternative names Recombinant Human Mesencephalic Astrocyte-Derived Neurotrophic Factor, His Tag, Mesencephalic astrocyte-derived neurotrophic factor, Protein ARMET, ARP, arginine-rich mutated in early stage tumors, Arginine-rich protein.
Purity >90%
Description His-Tag recombinant human MANF protein
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Solubility & Handling

Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >90%
Source E.coli.
Appearance Colourless solution (sterile filtered)
Formulation Solution (0.5mg/ml) containing Tris-HCl buffer (20mM, pH 8.0), NaCl (100mM), DTT (1mM) and 10% glycerol.

References for Recombinant human MANF (His Tag) protein

References are publications that support the biological activity of the product
  • Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats

    Renko JM et al (2018) Mol Neurobiol 55(8) : 6755-6768
  • Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease

    Voutilainen MH et al (2009) J Neurosci 29(30) : 9651-9
  • MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons

    Petrova P et al (2003) J Mol Neurosci 20(2) : 173-88

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