Recombinant human GFRA1 protein

(HB8712)
Technical documents: Datasheet

Product overview

Name Recombinant human GFRA1 protein
Alternative names Recombinant Human GDNF Family Receptor Alpha 1, GDNF receptor alpha-1, GDNFR-alpha-1, GFRalpha-1, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1, GDNFRA1, RET1L2, RETL1, Glial Cell LineDerived Neurotrophic Factor Receptor Alpha, TRNR1, GPILinked Anchor Protein, PI-Linked Cell-Surface.
Purity >95%
Description Recombinant human GDNF receptor alpha-1 protein
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Solubility & Handling

Solubility overview To make a working stock solution, add deionized water to make a solution (0.5mg/mL) and allow the lyophilized material to dissolve. Filter the product using an appropriate sterile filter before using it in cell culture
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • Freeze-thaw cycles should be prevented.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
UniProt ID P56159
Source HEK293 cells.
Structure image  Chemical Structure
Appearance White lyophilized powder (filtered & freeze-dried)
Formulation Filtered (0.4 µm) and lyophilized from a solution (0.5mg/ml) containing PBS (pH 7.5) with 5 % (w/v) trehalose

References for Recombinant human GFRA1 protein

References are publications that support the biological activity of the product
  • Biology of GDNF and its receptors - Relevance for disorders of the central nervous system

    Ibanez CF et al (2017) Neurobiol Dis 97(Pt B) : 80-89
  • Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM)

    Euteneuer S et al (2013) Mol Cell Neurosci 54 : 30-43
  • Glial cell line-derived neurotrophic factor (GDNF): a drug candidate for the treatment of Parkinson's disease

    Grondin R et al (1998) J Neurol 245(11 Suppl 3) : P35-42

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