Recombinant human GFRA1 protein

(HB8712)
Technical documents: Datasheet

Product overview

Name Recombinant human GFRA1 protein
Alternative names Recombinant Human GDNF Family Receptor Alpha 1, GDNF receptor alpha-1, GDNFR-alpha-1, GFRalpha-1, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1, GDNFRA1, RET1L2, RETL1, Glial Cell LineDerived Neurotrophic Factor Receptor Alpha, TRNR1, GPILinked Anchor Protein, PI-Linked Cell-Surface.
Purity >95%
Description Recombinant human GDNF receptor alpha-1 protein
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Solubility & Handling

Solubility overview To make a working stock solution, add deionized water to make a solution (0.5mg/mL) and allow the lyophilized material to dissolve. Filter the product using an appropriate sterile filter before using it in cell culture
Handling
  • Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
  • Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
  • Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Source HEK293 cells.
Appearance White lyophilized powder (filtered & freeze-dried)
Formulation Filtered (0.4 µm) and lyophilized from a solution (0.5mg/ml) containing PBS (pH 7.5) with 5 % (w/v) trehalose

References for Recombinant human GFRA1 protein

References are publications that support the biological activity of the product
  • Biology of GDNF and its receptors - Relevance for disorders of the central nervous system

    Ibanez CF et al (2017) Neurobiol Dis 97(Pt B) : 80-89
  • Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM)

    Euteneuer S et al (2013) Mol Cell Neurosci 54 : 30-43
  • Glial cell line-derived neurotrophic factor (GDNF): a drug candidate for the treatment of Parkinson's disease

    Grondin R et al (1998) J Neurol 245(11 Suppl 3) : P35-42

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