Recombinant human BDNF (His Tag) protein

(HB7742)

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Product overview

Name Recombinant human BDNF (His Tag) protein
Alternative names Recombinant Human Brain-Derived Neurotrophic Factor, His Tag, Brain-Derived Neurotrophic Factor, Neurotrophin, Abrineurin,ANON2, BULN2, Brain-derived neurotrophic factor.
Purity >85%
Description His tag recombinant human BDNF protein
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Solubility & Handling

Handling
  • Following reconstitution, solutions may be stored at 4°C if being used withing 2-4 weeks. For future use store at -20°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >85%
UniProt ID P23560
Source E. Coli.
Structure image  Chemical Structure
Appearance Colourless solution (sterile filtered)
Formulation Solution (1mg/ml) containing Tris-HCl buffer (20mM, pH 8.0) and 10% glycerol

References for Recombinant human BDNF (His Tag) protein

References are publications that support the biological activity of the product
  • The ability of BDNF to modify neurogenesis and depressive-like behaviors is dependent upon phosphorylation of tyrosine residues 365/367 in the GABA(A)-receptor γ2 subunit

    Vithlani M et al (2013) J Neurosci 33(39) : 15567-77
  • BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis

    Bramham CR et al (2005) Prog Neurobiol 76(2) : 99-125
  • Brain-derived neurotrophic factor

    Binder DK et al (2004) Growth Factors 22(3) : 123-31
  • Neurotrophins: roles in neuronal development and function

    Huang EJ et al (2001) Annu Rev Neurosci 24 : 677-736
  • Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF

    Ip NY et al (1993) J Neurosci 13(8) : 3394-405

5 Item(s)