Recombinant human BDNF (His Tag) protein

(HB7742)
Technical documents: Datasheet

Product overview

Name Recombinant human BDNF (His Tag) protein
Alternative names Recombinant Human Brain-Derived Neurotrophic Factor, His Tag, Brain-Derived Neurotrophic Factor, Neurotrophin, Abrineurin,ANON2, BULN2, Brain-derived neurotrophic factor.
Purity >85%
Description His tag recombinant human BDNF protein
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Solubility & Handling

Handling
  • Following reconstitution, solutions may be stored at 4°C if being used withing 2-4 weeks. For future use store at -20°C.
  • For long term storage, a carrier protein (0.1% HSA or BSA) should be added to stock solutions. Solutions should be aliquoted into tightly sealed vials for storage at -20°C. Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >85%
Source E. Coli.
Appearance Colourless solution (sterile filtered)
Formulation Solution (1mg/ml) containing Tris-HCl buffer (20mM, pH 8.0) and 10% glycerol

References for Recombinant human BDNF (His Tag) protein

References are publications that support the biological activity of the product
  • The ability of BDNF to modify neurogenesis and depressive-like behaviors is dependent upon phosphorylation of tyrosine residues 365/367 in the GABA(A)-receptor γ2 subunit

    Vithlani M et al (2013) J Neurosci 33(39) : 15567-77
  • BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis

    Bramham CR et al (2005) Prog Neurobiol 76(2) : 99-125
  • Brain-derived neurotrophic factor

    Binder DK et al (2004) Growth Factors 22(3) : 123-31
  • Neurotrophins: roles in neuronal development and function

    Huang EJ et al (2001) Annu Rev Neurosci 24 : 677-736
  • Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF

    Ip NY et al (1993) J Neurosci 13(8) : 3394-405

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