Recombinant human BDNF (HEK expressed) protein

(HB6907)

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Product overview

Name Recombinant human BDNF (HEK expressed) protein
Alternative names Brain-Derived Neurotrophic Factor Human Recombinant, HEK, Brain-Derived Neurotrophic Factor, BDNF, MGC34632, Abrineurin, ANON2, BULN2.
Purity >95%
Description HEK expressed recombinant human BDNF protein
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Solubility & Handling

Solubility overview To make a working stock solution, add deionized water to make a solution (0.5mg/mL) and allow the lyophilized material to dissolve
Handling
  • Following reconstitution, solutions may be stored at 4°C and are useable for a limited period of time. For future use store at -18°C.
  • Freeze-thaw cycles should be prevented.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >95%
UniProt ID P23560
Chemical structure  Chemical Structure
Source HEK293 Cells.
Appearance White lyophilized powder (filtered & freeze-dried)
Formulation Lyophilized & filtered (0.4μm) from from 0.5mg/ml in PBS

References for Recombinant human BDNF (HEK expressed) protein

References are publications that support the biological activity of the product
  • The ability of BDNF to modify neurogenesis and depressive-like behaviors is dependent upon phosphorylation of tyrosine residues 365/367 in the GABA(A)-receptor γ2 subunit

    Vithlani M et al (2013) J Neurosci 33(39) : 15567-77
  • BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis

    Bramham CR et al (2005) Prog Neurobiol 76(2) : 99-125
  • Brain-derived neurotrophic factor

    Binder DK et al (2004) Growth Factors 22(3) : 123-31
  • Neurotrophins: roles in neuronal development and function

    Huang EJ et al (2001) Annu Rev Neurosci 24 : 677-736
  • Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF

    Ip NY et al (1993) J Neurosci 13(8) : 3394-405

5 Item(s)