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Solubility & Handling Solubility overview To make a working stock solution, add deionized water to make a solution (0.5mg/mL) and allow the lyophilized material to dissolve
Handling
Following reconstitution, solutions may be stored at 4°C and are useable for a limited period of time. For future use store at -18°C.
Freeze-thaw cycles should be prevented.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Appearance White lyophilized powder (filtered & freeze-dried)
Formulation Lyophilized & filtered (0.4μm) from from 0.5mg/ml in PBS
References for Recombinant human BDNF (HEK expressed) protein References are publications that support the biological activity of the product
The ability of BDNF to modify neurogenesis and depressive-like behaviors is dependent upon phosphorylation of tyrosine residues 365/367 in the GABA(A)-receptor γ2 subunit Vithlani M et al (2013) J Neurosci 33(39) : 15567-77 BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis Bramham CR et al (2005) Prog Neurobiol 76(2) : 99-125 Brain-derived neurotrophic factor Binder DK et al (2004) Growth Factors 22(3) : 123-31 Neurotrophins: roles in neuronal development and function Huang EJ et al (2001) Annu Rev Neurosci 24 : 677-736 Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF Ip NY et al (1993) J Neurosci 13(8) : 3394-405
HEK expressed recombinant human BDNF protein
