PD-1 antagonist which shows equipotent PD-L1 and PD-L2 antagonism in rescue of lymphocyte proliferation and effector functions. Inhibits primary tumor growth and metastasis in melanoma, colon cancer and kidney cancer models. Exhibits immune activation and anti-tumor activity.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in water
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.
Understanding purity and quality - a guide for life scientists
