Product overview

Name AUNP-12 (NP-12)
Purity >95%
Description PD-1 antagonist. Immune checkpoint modulator.
Write Your Own Review
You're reviewing:AUNP-12 (NP-12)
Rate this item:

Biological Data

Biological description PD-1 antagonist which shows equipotent PD-L1 and PD-L2 antagonism in rescue of lymphocyte proliferation and effector functions. Inhibits primary tumor growth and metastasis in melanoma, colon cancer and kidney cancer models. Exhibits immune activation and anti-tumor activity.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.



More Info


More Info

Chemical Data

Purity >95%
Molecular Weight 3261.55
Molecular Formula C142H226N40O48
CAS Number 1353563-85-5

References for AUNP-12 (NP-12)

References are publications that support the biological activity of the product
  • A Rationally Designed Peptide Antagonist of the PD-1 Signaling Pathway as an Immunomodulatory Agent for Cancer Therapy.

    Sasikumar PG et al (2019) Molecular cancer therapeutics 18 : 1081-1091

1 Item