Product overview

Name Ghrelin (rat)
Biological description

Overview

Ghrelin is an endogenous ghrelin (GHS) receptor agonist and is an orexigenic hormone.

Uses & applications

It stimulates growth hormone release from the pituitary gland and is involved in a range of biological activities.

For example, it stimulates appetite and food intake and regulates of growth hormone and insulin secretion.

Additionally, it is involved in glucose and energy homeostasis, gastrointestinal motility, cardioprotection and neurogenesis.

Purity >95%
Description Endogenous hormone. Ghrelin receptor agonist.
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Solubility & Handling

Storage instructions -20°C (desiccate)
Solubility overview Soluble in water (1 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Chemical name GSSFLSPEHQKAQQRKESKKPPAKLQPR (Ser-3 = Ser(n-octanoyl))
Molecular Weight 3314.83
Chemical structure Ghrelin (rat) [258338-12-4] Chemical Structure
Molecular Formula C147H245N45O42
Sequence (one letter) GSSFLSPEHQKAQQRKESKKPPAKLQPR
Sequence (three letter) Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
Modifications Ser-3 = Ser(n-octanoyl)
CAS Number 258338-12-4
PubChem identifier 44134734
SMILES CCCCCCCC(=O)N(C(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)N2CCCC2C(=O)NC(CCC(=O)O)C(=O)NC(CC3=CNC=N3)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)N6CCCC6C(=O)NC(CCCNC(=N)N)C(=O)O)C(=O)C(CO)NC(=O)CN
InChiKey YQVMHOLUYGAYNG-UHFFFAOYSA-N
Protein length 29

References for Ghrelin (rat)

References are publications that support the biological activity of the product
  • An Integrative Review on Role and Mechanisms of Ghrelin in Stress, Anxiety and Depression

    Bali A et al (2016) Curr Drug Targets 17(5) : 495-507
  • Ghrelin: much more than a hunger hormone

    Pradhan G et al (2013) Curr Opin Clin Nutr Metab Care 16(6) : 619-24
  • Ghrelin: integrative neuroendocrine peptide in health and disease

    Wu JT et al (2004) Ann Surg 239(4) : 464-74

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