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Solubility & Handling Storage instructions -20°C (desiccate)
Solubility overview Soluble in water (1 mg/ml)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Chemical Data Chemical name CSCSSLMDKECVYFCHLDIIW
(Disulfide bridge between 1 - 15, 3 - 11)
Chemical structure
Molecular Formula C109 H159 N25 O32 S5
Sequence (one letter) CSCSSLMDKECVYFCHLDIIW
Sequence (three letter) Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp
Modifications Disulfide bridge between 1 - 15, 3 - 11
PubChem identifier 16133807
SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@@H]4CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H]5CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC5=O)CO)CO)CC(C)C)CCSC)CC(=O)O)CCCCN)CCC(=O)O)CO)N
InChiKey ZUBDGKVDJUIMQQ-ZTNLKOGPSA-N
References for Endothelin 1 (human, porcine) References are publications that support the biological activity of the product
Endothelin-1: Biosynthesis, Signaling and Vasoreactivity. Houde et al (2016) Adv Pharmacol 77 : 143-75 The role of endothelin-1 and endothelin receptor antagonists in inflammatory response and sepsis. Kowalczyk et al (2015) Arch Immunol Ther Exp (Warsz) 63(1) : 41-52 Endothelin-1: the yin and yang on vascular function. Marasciulo et al (2006) Curr Med Chem 13(14) : 1655-65
Endogenous vasoconstrictor neuropeptide
![Endothelin 1 (human, porcine) [117399-94-7] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb3442_1.png "Endothelin 1 (human, porcine) [117399-94-7]")
Understanding purity and quality - a guide for life scientists
