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Solubility & Handling
| Storage instructions | -20°C (desiccate) |
| Solubility overview | Soluble in water (1 mg/ml) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use |
Chemical Data
| Chemical name | CSCSSWLDKECVYFCHLDIIW
Disulfide bridge between 1 - 15, 3 - 11 |
| Chemical structure | ![Endothelin 2 (human) [123562-20-9] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Endothelin 2 (human) [123562-20-9]") |
| Molecular Formula | C115H160N26O32S4 |
| Sequence (one letter) | CSCSSWLDKECVYFCHLDIIW |
| Sequence (three letter) | Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp |
| Modifications | Disulfide bridge between 1 - 15, 3 - 11 |
| PubChem identifier | 16133808 |
| SMILES | CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@@H]4CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H]5CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC5=O)CO)CO)CC8=CNC9=CC=CC=C98)CC(C)C)CC(=O)O)CCCCN)CCC(=O)O)CO)N |
| InChiKey | MLFJHYIHIKEBTQ-IYRKOGFYSA-N |
References for Endothelin 2 (human)
References are publications that support the biological activity of the product
-
Endothelin-2, the forgotten isoform: emerging role in the cardiovascular system, ovarian development, immunology and cancer
Ling L et al (2013) Br J Pharmacol 168(2) : 283-95 -
Endothelin-1 and endothelin-2 initiate and maintain contractile responses by different mechanisms in rat mesenteric and cerebral arteries
Compeer MG et al (2013) Br J Pharmacol 170(6) : 1199-209 -
The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes
Inoue A et al (1989) Proc Natl Acad Sci U S A 86(8) : 2863-7
Vasoconstrictive neuropeptide.
![Endothelin 2 (human) [123562-20-9] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb3267_1.png "Endothelin 2 (human) [123562-20-9]")
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