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Solubility & Handling Storage instructions -20°C (desiccate)
Solubility overview Soluble in water (1 mg/ml)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Chemical Data Chemical name CSCSSWLDKECVYFCHLDIIW
Disulfide bridge between 1 - 15, 3 - 11
Chemical structure
Molecular Formula C115 H160 N26 O32 S4
Sequence (one letter) CSCSSWLDKECVYFCHLDIIW
Sequence (three letter) Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp
Modifications Disulfide bridge between 1 - 15, 3 - 11
PubChem identifier 16133808
SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@@H]4CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H]5CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC5=O)CO)CO)CC8=CNC9=CC=CC=C98)CC(C)C)CC(=O)O)CCCCN)CCC(=O)O)CO)N
InChiKey MLFJHYIHIKEBTQ-IYRKOGFYSA-N
References for Endothelin 2 (human) References are publications that support the biological activity of the product
Endothelin-2, the forgotten isoform: emerging role in the cardiovascular system, ovarian development, immunology and cancer Ling L et al (2013) Br J Pharmacol 168(2) : 283-95 Endothelin-1 and endothelin-2 initiate and maintain contractile responses by different mechanisms in rat mesenteric and cerebral arteries Compeer MG et al (2013) Br J Pharmacol 170(6) : 1199-209 The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes Inoue A et al (1989) Proc Natl Acad Sci U S A 86(8) : 2863-7
Vasoconstrictive neuropeptide.
![Endothelin 2 (human) [123562-20-9] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb3267_1.png "Endothelin 2 (human) [123562-20-9]")
Understanding purity and quality - a guide for life scientists
