Product overview

Name SHLP2
Purity >95%
Description Endogenous mitochondrial-derived peptide
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Biological Data

Biological description

Endogenous mitochondrial-derived peptide which is implicated in various biological processes such as aging and neurodegeneration. Enhances mitochondrial function and cell survival. Induces β-Arrestin recruitment to CXCR7 (EC50 = 0.97M) and directly binds to the receptor to cause its internalization. Suppresses food intake, prevents diet-induced obesity in mice and improves glucose tolerance and insulin sensitivity in vivo.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in PBS (1mg/ml), and in DMSO
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >95%
Molecular Weight 3015.58
Molecular Formula C142H214N36O35S

References for SHLP2

References are publications that support the biological activity of the product
  • Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers.

    Cobb LJ et al (2016) Aging 8 : 796-809

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