ROCK (Rho-kinase)

Potent, reversible AMPK activator. Inhibits MSC proliferation.

Sustains ESC self-renewal and pluripotency

Wnt pathway activator. Maintains ESC pluripotency in Wnt3a treated cells.

Endogenous prostanoid. Induces hematopoietic stem cell proliferation. 3D growth matrix component and used in production of liver and prostate organoids.