Cell permeable MAPKAPK2 (MK2) inhibitor which targets the MK2 substrate-binding site. Shown to ameliorate memory deficit induced by Aβ1-42 or lipopolysaccharide in novel object and location tasks. Reduces cardiac and pulmonary fibrosis and ammeliorates lung inflammation. Also attenuates DSS-induced body weight loss, colon length shortening, and colonic pathological injury in DSS induced models of acute colitis.
Solubility & Handling
Solubility overview
Soluble in PBS (1 mg/ml), and in DMSO
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists
