Cell permeable MAPKAPK2 (MK2) inhibitor which targets the MK2 substrate-binding site. Shown to ameliorate memory deficit induced by Aβ1-42 or lipopolysaccharide in novel object and location tasks. Reduces cardiac and pulmonary fibrosis and ammeliorates lung inflammation. Also attenuates DSS-induced body weight loss, colon length shortening, and colonic pathological injury in DSS induced models of acute colitis.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in PBS (1 mg/ml), and in DMSO
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists
