High affinity, selective 5-HT2B receptor antagonist with selectivity over 5-HT2A and 5-HT2C receptors (Ki values are 0.75, 21.63 and 28.7 nM at 5-HT2B, 5-HT2C and 5-HT2A receptors respectively). Active in vivo and orally active. Displays antihypertensive activity.
Solubility & Handling
Solubility overview
Soluble in DMSO (100 mM), and in ethanol (10 mM)
Storage instructions
 +4°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use