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Polymyxin B Sulfate

(HB0530)
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Technical documents: Datasheet
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Product overview

Name Polymyxin B Sulfate
Description Cationic antimicrobial peptide
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description Cationic antimicrobial peptide. Mixture of polymyxin components such as B1 and B2. Displays high affinity for lipopolysaccharide (LPS) and causes LPS aggregation. Shows bactericidal antibiotic actions against gram-negative bacteria.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (50mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Chemical name Aerosporin
Molecular Weight 1385.6
Molecular Formula C55H96N16O13.2H2SO4
CAS Number 1405-20-5
SMILES CC(C)CC1NC(=O)C(Cc2ccccc2)NC(=O)C(CCN)NC(=O)C(CCNC(=O)C(CCO)NC(=O)C(CCN)NC(=O)C(CCN)NC1=O)NC(=O)C(CCN)NC(=O)C(CCO)NC(=O)C(CCN)NC=O.O[S](O)(=O)=O

References for Polymyxin B Sulfate

References are publications that support the biological activity of the product

  • Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission.

    Rolin O et al (2014) Infect Immun 82(2) : 491-9.
    Read more (PubMedID: 24478065)

  • Biophysical characterization of polymyxin B interaction with LPS aggregates and membrane model systems.

    Domingues MM et al (2012) Biopolymers 98(4) : 338-44.
    Read more (PubMedID: 23193598)

  • In vitro potency of various polymyxin B components.

    Tam VH et al (2011) Antimicrob Agents Chemother 55(9) : 4490-1.
    Read more (PubMedID: 21709096)

3 Item(s)

Grouped product items
Order: HB0530
Pack PriceQty
1g
$248
5g
$980
Cationic antimicrobial peptide
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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