Product overview

Name Pepstatin A
Purity >98%
Description Aspartic protease inhibitor
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Biological Data

Biological description Aspartic protease inhibitor. Widely used as a research tool in studies of protease mechanisms and biological functions. Inhibits degradation of autophagic cargo inside autophagolysosomes.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.



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Chemical Data

Purity >98%
Molecular Weight 685.9
Chemical structure Pepstatin A [26305-03-3] Chemical Structure
Molecular Formula C34H63N5O9
CAS Number 26305-03-3
PubChem identifier 5478883
SMILES O=C(N[C@@H](CC(C)C)[C@@H](O)CC(N[C@@H](C)C(N[C@H]([C@@H](O)CC(O)=O)CC(C)C)=O)=O)[C@H]([C@@H](C)C)NC([C@@H](NC(CC(C)C)=O)C(C)C)=O
Appearance White to off-white powder

References for Pepstatin A

References are publications that support the biological activity of the product
  • Pepstatin A Alters Host Cell Autophagic Machinery and Leads to a Decrease in Influenza A Virus Production

    Matarrese et al (2011) J Cell Physiol 226(12) : 3368-77
  • Pepstatin A, an Aspartic Proteinase Inhibitor, Suppresses RANKL-induced Osteoclast Differentiation

    Yoshida et al (2006) J Biochem 139(3) : 583-90
  • Pepstatin, a New Pepsin Inhibitor Produced by Actinomycetes

    Umezawa et al (1970) J Antibiot (Tokyo) 23(5) : 259-62

3 Item(s)