Potent and selective BRD4 bromodomain inhibitor (Ki = 30-50 nM). Selective for the first over the second bromodomain. Inhibits the activity of BRD4 in macrophage nitric oxide and Il-6 production. Alters colony integrity in embryonic stem cells. Shows antiproliferative and anticancer actions.
Solubility & Handling
Solubility overview
Soluble in DMSO (100mM)
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.