Product overview

Name mCRAMP (mouse)
Biological description

Only identified mouse cathelicidin and LL 37 (human) homolog. Displays chemotactic effects (e.g. for monocytes, neutrophils and macrophages) and enhances the adaptive immune response. Down-regulates LPA-induced innate immune responses and shows angiogenic, antimicrobial and antiviral activity.

Alternative names Mouse calethicidin related antimicrobial peptide
Purity >95%

Mouse cathelicidin. LL 37 (human) ortholog.

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Solubility & Handling

Storage instructions -20°C
Solubility overview

Soluble in aqueous buffer

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use



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Chemical Data

Purity >95%
Molecular Weight 3878.65
Molecular Formula C178H302N50O46
Sequence (three letter) H-Gly-Leu-Leu-Arg-Lys-Gly-Gly-Glu-Lys-Ile-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-Val-Pro-Gln-Pro-Glu-Gln-OH

References for mCRAMP (mouse)

References are publications that support the biological activity of the product
  • The Antimicrobial Cathelicidin CRAMP Augments Platelet Activation during Psoriasis in Mice

    Salamah MF et al (2020) Biomolecules 10(9) : 0
  • Short, Synthetic Cationic Peptides Have Antibacterial Activity against Mycobacterium smegmatis by Forming Pores in Membrane and Synergizing with Antibiotics

    Gupta K et al (2015) Antibiotics (Basel) 4(3) : 358-78
  • The human antimicrobial peptide LL-37, but not the mouse ortholog, mCRAMP, can stimulate signaling by poly(I:C) through a FPRL1-dependent pathway

    Singh D et al (2013) J Biol Chem 288(12) : 8258-8268
  • Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens

    Iimura M et al (2005) J Immunol 174(8) : 4901-7

4 Item(s)