Product overview

Name LL-37 (13-37) (human)
Biological description

Peptide fragment of LL-37 (human). Shows antibacterial, antifungal and antiviral activity. Also inhibits proliferation of drug-resistant and drug-sensitive carcinoma cells to show anticancer activity.

Alternative names IG-27
Purity >95%
Description

Peptide fragment of LL-37 (human)

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Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in acidic buffer
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

Purity >95%
Molecular Weight 3043.6
Molecular Formula

C137H232N42O36

Sequence (one letter) IGKEFKRIVQRIKDFLRNLVPRTES
Sequence (three letter) H-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH

References for LL-37 (13-37) (human)

References are publications that support the biological activity of the product
  • Roles and Mechanisms of Human Cathelicidin LL-37 in Cancer

    Chen X et al (2018) Cell Physiol Biochem 47(3) : 1060-1073
  • Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease

    Kahlenberg JM et al (2013) J Immunol 191(10) : 4895-901
  • Solution structures of human LL-37 fragments and NMR-based identification of a minimal membrane-targeting antimicrobial and anticancer region

    Li X et al (2006) J Am Chem Soc 128(17) : 5776-85

3 Item(s)