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Biological Data Biological description Competitive Tryptophan 2-monooxygenase inhibitor. Intermediate of indole-3-acetic acid formation from L-tryptophan. Detoxifies several growth inhibiting tryptophan analogs.
Solubility & Handling Solubility overview Soluble in methanol
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical structure
Molecular Formula C10 H10 N2 O
SMILES C1=CC=C2C(=C1)C(=CN2)CC(=O)N
References for Indole-3-acetamide References are publications that support the biological activity of the product
Characterization of 2-oxo-3-pentynoate as an active-site-directed inactivator of flavoprotein oxidases: identification of active-site peptides in tryptophan 2-monooxygenase. Gadda G et al (1999) Biochemistry 38(18) : 5822-8. Indole inhibitors of human nonpancreatic secretory phospholipase A2. 1. Indole-3-acetamides. Dillard RD et al (1996) J Med Chem 39(26) : 5119-36. Biosynthesis of indole-3-acetic acid via the indole-3-acetamide pathway in Streptomyces spp. Manulis S et al (1994) Microbiology 140 ( Pt 5) : 1045-50.
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Competitive Tryptophan 2-monooxygenase oxidase inhibitor