Product overview

Name Heliquinomycin
Purity >80%
Description DNA helicase inhibitor
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Biological Data

Biological description Antibiotic. DNA helicase inhibitor. Inhibits the DNA helicase activity of the human minichromosome maintenance (MCM) 4/6/7 complex. Topoisomerase I and II inhibitor (weaker than DNA helicase). DNA and RNA synthesis inhibitor in cell culture. Does not inhibit protein synthesis. Induces cell cycle arrest. Anticancer compound. Antibacterial against Gram-positive bacteria.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >80%
Molecular Weight 698.6
Chemical structure Heliquinomycin [178182-49-5] Chemical Structure
CAS Number 178182-49-5
SMILES COC1CC(OC(C)C1O)O[C@@H]2c3c(O)c4C(=O)C=C(OC)C(=O)c4c(O)c3O[C@@]25Oc6c(O)c7C(=O)OC(=Cc7cc6C[C@H]5O)C(=O)OC
InChiKey MLFZQFHGXSVTGX-VJANPNJTSA-N
Appearance Red powder