GluA1-4 Antibody (ValidAb™): Pan-AMPA Antibody for Total AMPAR Detection

Fluorescent image showing AMPA receptor expression in rat dentate gyrus and CA1 using Hello Bio GluA1-4 Antibody (HB7534)

 Introduction Applications  Highlights Try AntiGluA1–4 (Pan-AMPAR) Antibody ★ 

 

A new validated pan-AMPAR antibody for GluA1–4 detection. Exclusively from Hello Bio

Advance your AMPAR research with the GluA1–4 Antibody (ValidAb™) – a rigorously validated rabbit polyclonal antibody that recognises all four AMPA receptor subunits (GluA1–4). It’s a valuable addition to your glutamate receptor toolkit and part of our trusted ValidAb™ range – known for reproducibility and transparent performance.

 

Explore Anti-GluA1–4 ValidAb   

 

Why this antibody stands out:

✔ Rabbit origin offers real performance advantages
This is the only anti-pan-AMPA antibody available from a rabbit host — giving you higher affinity, greater sensitivity, and lower background in rodent samples. It's ideal for detecting low-abundance AMPARs, co-staining alongside mouse antibodies, and producing clearer, more specific ICC and WB results. Whether you're working with complex tissues or subtle receptor changes, rabbit-derived antibodies offer a smarter alternative for in vitro AMPAR studies.

Validation you can trust
Existing tools lack robust testing or show unexpected localisation. This antibody is different: it's validated for western blot , IHC and ICC, and produces clear dendritic receptor clustering – precisely where AMPARs should localise. No nuclear artefacts. No ambiguous signal. Just confidence in your results.

Part of our ValidAb™ range
All ValidAb™ antibodies meet stringent in-house QC benchmarks to ensure strong, specific signal, low background, and reproducible results — helping you move forward with fewer technical uncertainties.

A new tool for AMPA receptor studies
This antibody expands the limited selection of pan-AMPAR tools available. With stronger validation and trusted specificity, it offers a more reliable choice for researchers studying glutamate receptor signalling.

 

Ideal for:


Quantifying total AMPA receptor expression

✔  Visualising AMPAR localisation in dendrites

✔ Normalising subunit-specific expression data — e.g. calculating GluA1/GluA1–4 to assess relative expression

✔  In vitro applications including ICC, IHC and western blot

Scientists needing updated, trustworthy AMPAR tools

 

Highlights at a glance

  • Recognises GluA1–4 in a single assay
  • ICC images show clear dendritic clustering
  • Validated for western blot, IHC and ICC
  • Exclusive to Hello Bio - excellent value, exceptional performance

 

Order Anti-GluA1–4 ValidAb   

 

See it in action: ICC data shows beautiful dendritic AMPAR localisation

Looking for more antibodies with the same rigorous validation? Explore the full ValidAb™ range.

 

References

  1. Molnar E et al (2002) Developmental and activity dependent regulation of ionotropic glutamate receptors at synapses.
    TheScientificWorldJournal 2 : 27-47 PMC12806037
  2. Nusser Z et al (1998) Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus.
    Neuron 21 : 545-59 Read more PMC 9768841
  3. Baude A et al (1995) High-resolution immunogold localization of AMPA type glutamate receptor subunits at synaptic and non-synaptic sites in rat hippocampus.
    Neuroscience 69 : 1031-55 Read more PMC 8848093