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Biological Data
| Biological description | Potent, selective and covalent Methionine aminopeptidase-2 (MetAP2) inhibitor. Impairs endothelial cell growth and alters gene expression. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo. Shows anti-angiogenisis, antiviral, anticancer, antimicrobial, antimalarial and amoebicidal activity. |
Solubility & Handling
| Storage instructions | +4°C |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical structure | ![Fumagillin [23110-15-8] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Fumagillin [23110-15-8]") |
| Molecular Formula | C26H34O7 |
| PubChem identifier | 6917655 |
| SMILES | [H][C@@]1([C@]3(C)[C@@H](C/C=C(C)/C)O3)[C@@]2(CO2)CC[C@@H](OC(/C=C/C=C/C=C/C=C/C(O)=O)=O)[C@H]1OC |
| InChiKey | NGGMYCMLYOUNGM-IWMBURASSA-N |
| Appearance | Off-white solid |
Methionine aminopeptidase-2 inhibitor
![Fumagillin [23110-15-8] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb3901.png "Fumagillin [23110-15-8]")
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