Product overview

Name Fumagillin
Purity >98%
Description Methionine aminopeptidase-2 inhibitor
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Biological Data

Biological description Potent, selective and covalent Methionine aminopeptidase-2 (MetAP2) inhibitor. Impairs endothelial cell growth and alters gene expression. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo. Shows anti-angiogenisis, antiviral, anticancer, antimicrobial, antimalarial and amoebicidal activity.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >98%
Molecular Weight 458.6
Chemical structure Fumagillin [23110-15-8] Chemical Structure
Molecular Formula C26H34O7
CAS Number 23110-15-8
PubChem identifier 6917655
SMILES [H][C@@]1([C@]3(C)[C@@H](C/C=C(C)/C)O3)[C@@]2(CO2)CC[C@@H](OC(/C=C/C=C/C=C/C=C/C(O)=O)=O)[C@H]1OC
InChiKey NGGMYCMLYOUNGM-IWMBURASSA-N
Appearance Off-white solid