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Biological Data
Biological description | Prenylated 4-hydroxycoumarin. Anti-tumor compound. Cytotoxic. Stimulator of tubulin polymerisation in vitro. Inhibitor of colchicine binding to tubulin. Antitubercular antibiotic with potent antibacterial activity. Anti-coagulant, pro-haemorrhagic compound with higher activity than warfarin. Shows hepatocyte toxicity. Disrupts mitochondrial membrane potential. |
Solubility & Handling
Storage instructions | +4°C |
Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
Chemical name | 2-Hydroxy-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-4-one |
Chemical structure | |
SMILES | CC(C)=CCC\C(C)=C\CC\C(C)=C\CC1=C(O)Oc2ccccc2C1=O |
InChiKey | AHXOQKFWHSHTOS-RTIZFMKRSA-N |
Appearance | White to off-white solid |
Anti-tumor compound and tubulin polymerisation stimulator.