Product overview

Name Eupatilin
Purity >98%
Description Selective 5-lipoxygenase (5-LOX) inhibitor
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Biological Data

Biological description Selective inhibitor of 5-lipoxygenase. Apoptosis and cell cycle arrest inducer. Anticancer compound. Inhibits ERK1/2, JNK, and NF-kappaB activation and expression of Raf-1 and Ras. Anti-proliferative compound. Anti-inflammatory and immunosuppressive. Anti-apoptotic compound in hepatocytes. Antioxidant. Antidiabetic. Enhances hepatic and plasma glucose metabolism and increases insulin secretion in type 2 diabetic mice. Inhibits angiogenesis by blocking STAT3 and VEGF expression. Neuroprotective. PI3K Class I, MKK3/6 and MKK4 inhibitor.

Solubility & Handling

Storage instructions +4°C
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >98%
Chemical name 5,7-Dihydroxy-3',4',6-trimethoxyflavone
Molecular Weight 344.3
Chemical structure Eupatilin [22368-21-4] Chemical Structure
CAS Number 22368-21-4
SMILES COc1ccc(cc1OC)C2=CC(=O)c3c(O)c(OC)c(O)cc3O2
InChiKey DRRWBCNQOKKKOL-UHFFFAOYSA-N
Appearance Pale yellow powder