Eupatilin

(HB3894)

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Product overview

Name Eupatilin
Purity >98%
Description Selective 5-lipoxygenase (5-LOX) inhibitor
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Biological Data

Biological description Selective inhibitor of 5-lipoxygenase. Apoptosis and cell cycle arrest inducer. Anticancer compound. Inhibits ERK1/2, JNK, and NF-kappaB activation and expression of Raf-1 and Ras. Anti-proliferative compound. Anti-inflammatory and immunosuppressive. Anti-apoptotic compound in hepatocytes. Antioxidant. Antidiabetic. Enhances hepatic and plasma glucose metabolism and increases insulin secretion in type 2 diabetic mice. Inhibits angiogenesis by blocking STAT3 and VEGF expression. Neuroprotective. PI3K Class I, MKK3/6 and MKK4 inhibitor.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name 5,7-Dihydroxy-3',4',6-trimethoxyflavone
Molecular Weight 344.3
Chemical structure Eupatilin [22368-21-4] Chemical Structure
CAS Number 22368-21-4
SMILES COc1ccc(cc1OC)C2=CC(=O)c3c(O)c(OC)c(O)cc3O2
InChiKey DRRWBCNQOKKKOL-UHFFFAOYSA-N
Appearance Pale yellow powder