D-erythro-Sphingosine

Name: D-erythro-Sphingosine
SKU: HB0239
Price: 385 USD
Availability: InStock

(HB0239)

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Technical documents: Datasheet

Product overview

Name

D-erythro-Sphingosine

Purity

>98%

Description

PKC inhibitor

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) References (3)

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Biological Data

Biological description

Protein kinase C (PKC) inhibitor. Also TRPM3 channel activator (EC₅₀ = 12 µM). Exhibits little or no activity for other TRP channels. Also inhibits platelet aggregation.

Solubility & Handling

Solubility overview

Soluble in ethanol (25mg/ml, gentle warming) or DMSO (25mg/ml, methanol)

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>98%

Chemical name

Sphingosine, C18 chain

Molecular Weight

299.5

Molecular Formula

C₁₈H₃₇NO₂

CAS Number

123-78-4

PubChem identifier

5280335

SMILES

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for D-erythro-Sphingosine

References are publications that support the biological activity of the product

A concise synthesis of a promising protein kinase C inhibitor: D-erythro-sphingosine.
Pham VT et al (2007) Arch Pharm Res 30(1) : 22-7.
Read more (PubMedID: 17328238)
Activation of the melastatin-related cation channel TRPM3 by D-erythro-sphingosine [corrected].
Grimm C et al (2005) Mol Pharmacol 67(3) : 798-805.
Read more (PubMedID: 15550678)
Use of D-erythro-sphingosine as a pharmacological inhibitor of protein kinase C in human platelets.
Khan WA et al (1991) Biochem J 278 ( Pt 2) : 387-92.
Read more (PubMedID: 1898331)

PKC inhibitor

Order: HB0239
Pack	Price	Qty
50mg	$385
100mg	$717

D-erythro-Sphingosine

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for D-erythro-Sphingosine

A concise synthesis of a promising protein kinase C inhibitor: D-erythro-sphingosine.

Activation of the melastatin-related cation channel TRPM3 by D-erythro-sphingosine [corrected].

Use of D-erythro-sphingosine as a pharmacological inhibitor of protein kinase C in human platelets.

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D-erythro-Sphingosine

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for D-erythro-Sphingosine

A concise synthesis of a promising protein kinase C inhibitor: D-erythro-sphingosine.

Activation of the melastatin-related cation channel TRPM3 by D-erythro-sphingosine [corrected].

Use of D-erythro-sphingosine as a pharmacological inhibitor of protein kinase C in human platelets.

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Tell us about your publication!

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About you

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New Products in this Area