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Brilliant Blue G

(HB0716)
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Technical documents: SDS Datasheet
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Product overview

Name Brilliant Blue G
Alternative names Acid blue 90; Coomassie Brilliant Blue G; NSC 328382; CBBG
Biological description Non-competitive P2X7 antagonist (IC50 values are 10 and 200 nM at rat and human P2X7 respectively). Displays neuroprotective and anti-inflammatory properties. Also a protein binding dye causing a colour change from red to blue.
Description Non-competitive P2X7 antagonist. Protein-binding dye.
Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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Images

Brilliant Blue G product vial image | Hello Bio
Brilliant Blue G product vial image | Hello Bio

Brilliant Blue G product vial image | Hello Bio

Brilliant Blue G product vial image | Hello Bio

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (40mg/ml, at 20°C) or methanol
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Chemical name Coomassie Brilliant Blue G (CBBG)
Molecular Weight 854.02
Chemical structure Brilliant Blue G [6104-58-1] Chemical Structure
Molecular Formula C47H48N3NaO7S2
CAS Number 6104-58-1
PubChem identifier 6324599
SMILES CCN(CC1=CC(=CC=C1)S(=O)(=O)[O-])C2=CC(=C(C=C2)/C(=C/3\C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)[O-])C=C3C)/C5=CC=C(C=C5)NC6=CC=C(C=C6)OCC)C.[Na+]

References for Brilliant Blue G

References are publications that support the biological activity of the product

  • Block of purinergic P2X(7) receptor is neuroprotective in an animal model of Alzheimer's disease.

    Ryu JK et al (2008) Neuroreport 19(17) : 1715-9.
    Read more (PubMedID: 18852683)

  • Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors.

    Jiang LH et al (2000) Mol Pharmacol 58(1) : 82-8.
    Read more (PubMedID: 10860929)

  • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

    Bradford MM (1976) Anal Biochem 72 : 248-54.
    Read more (PubMedID: 942051)

3 Item(s)

Grouped product items
Order: HB0716
Pack PriceQty
1g
$49
Non-competitive P2X7 antagonist. Protein-binding dye.
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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