bpV(bipy)

Name: bpV(bipy)
SKU: HB0144
Price: 675 USD
Availability: InStock

(HB0144)

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Technical documents: Datasheet

Product overview

Name

bpV(bipy)

Purity

>95%

Description

Potent protein PTP inhibitor

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) References (4)

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Biological Data

Biological description

Potent protein phosphotyrosine phosphatase (PTP) inhibitor (IC₅₀ values are 18 and 164 nM for PTP-β and PTP-1B respectively). Also inhibits phosphatase and tensin homologue (PTEN) (IC₅₀ = 18 nM). Displays insulin-mimetic properties.

Solubility & Handling

Storage instructions

+4°C

Solubility overview

Soluble in water

Important

This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

More Info

Dilution

More Info

Chemical Data

Purity

>95%

Chemical name

Potassiumbisperoxo(bipyridine)oxovanadate(V)

Molecular Weight

326.2

Chemical structure

Molecular Formula

K[VO(O₂)₂C₁₀H₈N₂]

CAS Number

127393-89-9

SMILES

C[C@@H]1C[C@H](O)\C=C/[C@H](O)[C@@H](O)CC(=O)O1

Technical guides

Understanding purity and quality - a guide for life scientists (159.4 KB)

References for bpV(bipy)

References are publications that support the biological activity of the product

Bisperoxovanadium compounds are potent PTEN inhibitors.
Schmid AC et al (2004) FEBS Lett 566(1-3) : 35-8.
Read more (PubMedID: 15147864)
Inhibition Effects of Some Bioactive Peroxovanadium Complexes on the Tyrosine Phosphatase.
Zhou XW et al (2000) Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 32(2) : 133-138.
Read more (PubMedID: 12098789)
Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen).
Band CJ et al (1997) Mol Endocrinol 11(13) : 1899-910.
Read more (PubMedID: 9415395)
Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics.
Posner BI et al (1994) J Biol Chem 269(6) : 4596-604.
Read more (PubMedID: 8308031)

Potent protein PTP inhibitor

Order: HB0144
Pack	Price	Qty
25mg	$675

bpV(bipy)

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for bpV(bipy)

Bisperoxovanadium compounds are potent PTEN inhibitors.

Inhibition Effects of Some Bioactive Peroxovanadium Complexes on the Tyrosine Phosphatase.

Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen).

Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics.

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bpV(bipy)

Product overview

Biological Data

Solubility & Handling

Calculators

Molarity

Dilution

Chemical Data

Technical guides

References for bpV(bipy)

Bisperoxovanadium compounds are potent PTEN inhibitors.

Inhibition Effects of Some Bioactive Peroxovanadium Complexes on the Tyrosine Phosphatase.

Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen).

Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics.

About you

Tell us about your publication!

Captcha

About you

How can we help you?

New Products in this Area