URB 597

(HB2365)

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Product overview

Name URB 597
Purity >99%
Description Potent, selective FAAH inhibitor
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Biological Data

Biological description Potent and selective FAAH inhibitor (IC50 values are 4.6 and 0.5 nM in rat brain memebrane and cortical neurons respectively). Causes an accumulation of anandamide. Shows little activity at various cannabinoid related targets. Displays antidepressant, antinociceptive, anxiolytic and analgesic effects.

Solubility & Handling

Solubility overview Soluble in DMSO (50mM)
Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >99%
Chemical name Cyclohexylcarbamic acid 3'-(Aminocarbonyl)-[1,1'-biphenyl]-3- yl ester
Molecular Weight 338.4
Chemical structure URB 597 | [546141-08-6] Chemical Structure
Molecular Formula C20H22N2O3
CAS Number 546141-08-6
PubChem identifier 1383884
SMILES C1CCC(CC1)NC(=O)OC2=CC=CC(=C2)C3=CC(=CC=C3)C(=O)N
InChi InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
InChiKey ROFVXGGUISEHAM-UHFFFAOYSA-N
MDL number MFCD05863934