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Biological Data
Biological description | Mycotoxin. Alkaloid antibiotic. Bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor. Antineoplastic activity. Moderate cytotoxicity against A-549 and HL-60 cell lines. Induces cell cycle arrest through G2/M phase, presumably by inhibiting tubulin polymerization. Antifouling agent against the barnacle Balanus amphitrite. |
Solubility & Handling
Storage instructions | +4°C |
Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
Chemical structure | |
SMILES | CON1c2ccccc2C3(C=C(O)C(=O)N4C(=C\c5[nH]cnc5)/C(=O)NC134)C(C)(C)C=C |
InChiKey | JTJJJLSLKZFEPJ-ZAYCRUKZSA-N |
Appearance | Colorless to white adhered film |
Mycotoxin. Alkaloid antibiotic.