Product overview

Name Meleagrin
Purity >90%
Description Mycotoxin. Alkaloid antibiotic.
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Biological Data

Biological description Mycotoxin. Alkaloid antibiotic. Bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor. Antineoplastic activity. Moderate cytotoxicity against A-549 and HL-60 cell lines. Induces cell cycle arrest through G2/M phase, presumably by inhibiting tubulin polymerization. Antifouling agent against the barnacle Balanus amphitrite.

Solubility & Handling

Storage instructions +4°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >90%
Molecular Weight 433.5
Chemical structure Meleagrin [71751-77-4] Chemical Structure
CAS Number 71751-77-4
SMILES CON1c2ccccc2C3(C=C(O)C(=O)N4C(=C\c5[nH]cnc5)/C(=O)NC134)C(C)(C)C=C
InChiKey JTJJJLSLKZFEPJ-ZAYCRUKZSA-N
Appearance Colorless to white adhered film