Product overview

Biological description

Non-denaturing detergent which is frequently used for protein solubilization and stabilization.

Description Detergent for protein solubilization/ stabilization
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Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (100 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use



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Chemical Data

Chemical name 3-[(3-Cholamidopropyl)-dimethylammonio]-1-propanesulfonate
Molecular Weight 614.9
Chemical structure CHAPS | [75621-03-3] Chemical Structure
Molecular Formula C32H58N2O7S
CAS Number 75621-03-3
PubChem identifier 107670
SMILES C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C
InChi InChI=1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
MDL number MFCD00012116

References for CHAPS

References are publications that support the biological activity of the product
  • Evaluation of sodium deoxycholate as solubilization buffer for oil palm proteomics analysis

    Lau BYC et al (2019) PLoS One 14(8) : e0221052
  • Buffers more than buffering agent: introducing a new class of stabilizers for the protein BSA

    Gupta BS et al (2015) Phys Chem Chem Phys 17(2) : 1114-33
  • New pH-buffering system for media utilized during gamete and embryo manipulations for assisted reproduction

    Swain JE et al (2009) Reprod Biomed Online 18(6) : 799-810
  • The dual role of CHAPS in the crystallization of stromelysin-3 catalytic domain

    Gall AL et al (2003) Acta Crystallogr D Biol Crystallogr 59(Pt 3) : 603-6
  • CHAPS Solubilization and Functional Reconstitution of beta-Glucan Synthase from Red Beet Root (Beta vulgaris L.) Storage Tissue

    Sloan ME et al (1987) Plant Physiol 85(2) : 516-22

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