DREADDs

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 1-10 of 18

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  1. Description:

    Fluorescent 5-HT2A receptor antagonist

    Pack:
    50μg
    Price:
    $275
    Qty:
  2. Clozapine (HB1607)

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    Description:

    Prototypic, atypical antipsychotic, binds to both serotonin and dopamine receptors

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $20
    Qty:
    Pack:
    10mg
    Price:
    $28
    Qty:
    Pack:
    25mg
    Price:
    $55
    Qty:
    Pack:
    50mg
    Price:
    $88
    Qty:
    Pack:
    100mg
    Price:
    $132
    Qty:
    Pack:
    500mg
    Price:
    $476
    Qty:
  3. Description:

    Non-selective 5HT2 antagonist

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $63
    Qty:
  4. Gramine (HB0305)

    Description:

    5-HT2A receptor antagonist

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $460
    Qty:
  5. Pack:
    10mg
    Price:
    $139
    Qty:
    Pack:
    50mg
    Price:
    $601
    Qty:
  6. Pack:
    10mg
    Price:
    $263
    Qty:
    Pack:
    50mg
    Price:
    $1,003
    Qty:
  7. Metergoline (HB1623)

    Description:

    5-HT1/5-HT2 antagonist. Shows affinity for 5-HT6 and 5-HT7.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $87
    Qty:
    Pack:
    50mg
    Price:
    $257
    Qty:
  8. Description:

    Non-selective 5-HT2 receptor antagonist. Shows activity at other receptors.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $97
    Qty:
  9. Olanzapine (HB1786)

    Description:

    5-HT2A and D2 antagonist. Potent DREADD agonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $54
    Qty:
    Pack:
    50mg
    Price:
    $215
    Qty:
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