DREADDs
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
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Alprenolol hydrochloride (HB1734)
Description:Non-selective β-adrenoceptor antagonist. Also a 5-HT1A receptor antagonist.
Purity:>99%
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AM251 (HB2776)
Description:Potent, selective CB1 receptor antagonist / inverse agonist
Purity:>98%
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AM281 (HB2312)
Description:Potent, selective CB1 receptor antagonist / inverse agonist
Purity:>98%
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AMD 3100 octahydrochloride (HB2739)
Description:Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.
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Amisulpride (HB1879)
Description:Potent, selective dopamine D2 and D3 receptor antagonist. Atypical antipsychotic.
Purity:>98%
- Description:
Competitive fluorescent adenosine receptor antagonist
- Description:
Fluorescent A3 adenosine receptor antagonist
- Description:
Fluorescent β2 adrenoceptor antagonist
![CA200634 CellAura fluorescent adenosine antagonist [XAC]](https://hellobio.com/media/catalog/product/cache/7630ee9852b6c22c7de1165054afc779/h/b/hb7814-ca200634-image1_1.jpg)
![CA200645 CellAura fluorescent adenosine A<sub>3</sub> antagonist [XAC]](https://hellobio.com/media/catalog/product/cache/7630ee9852b6c22c7de1165054afc779/h/b/hb7812-ca200645-image1_1.png)
![CA200656 CellAura fluorescent β<sub>2</sub> antagonist [(±)-propranolol]](https://hellobio.com/media/catalog/product/cache/7630ee9852b6c22c7de1165054afc779/h/b/hb7820-ca200656-image1_1.jpg)