DREADDs

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

8 Items

Set Descending Direction
  1. Amisulpride (HB1879)

    Description:

    Potent, selective dopamine D2 and D3 receptor antagonist. Atypical antipsychotic.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $136
    Qty:
  2. Description:

    D2 receptor antagonist

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $156
    Qty:
    Pack:
    50mg
    Price:
    $587
    Qty:
  3. Olanzapine (HB1786)

    Description:

    5-HT2A and D2 antagonist. Potent DREADD agonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $54
    Qty:
    Pack:
    50mg
    Price:
    $215
    Qty:
  4. Paliperidone (HB1798)

    Description:

    5-HT2A and D2 antagonist. Antipsychotic.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $132
    Qty:
    Pack:
    50mg
    Price:
    $482
    Qty:
  5. Description:

    D2 receptor antagonist. Also 5-HT3 and nAChR antagonist.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $86
    Qty:
  6. Description:

    5-HT2 and D2 antagonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $132
    Qty:
  7. Description:

    5-HT2A and D2 antagonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $575
    Qty:
  8. Zotepine (HB1778)

    Description:

    5-HT2A and dopamine D2 receptor antagonist. Atypical antipsychotic.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $97
    Qty:
    Pack:
    50mg
    Price:
    $380
    Qty: