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DREADDs

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 1-10 of 19

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  1. [Ala11,D-Leu15]-Orexin B (HB3407)

    Description:

    Potent, selective OX2 receptor agonist

    [Ala11,D-Leu15]-Orexin B
    Pack:
    1mg
    Price:
    $274
    Qty:
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  2. BQ-123 (HB3213)

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    Description:

    Potent, selective ETA antagonist

    BQ-123
    Pack:
    500μg
    Price:
    $140
    Qty:
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  3. Endothelin 1 (human, porcine) (HB3442)

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    Description:

    Endogenous vasoconstrictor neuropeptide

    Endothelin 1 (human, porcine)
    Pack:
    100μg
    Price:
    $141
    Qty:
    Pack:
    500μg
    Price:
    $512
    Qty:
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  4. Endothelin 2 (human) (HB3267)

    Description:

    Vasoconstrictive neuropeptide.

    Endothelin 2 (human)
    Pack:
    100μg
    Price:
    $151
    Qty:
    Supporting Docs Add to Favorites

  5. Exendin-4 (HB3157)

    Description:

    Potent GLP-1 receptor agonist

    Exendin-4
    Pack:
    500μg
    Price:
    $196
    Qty:
    Pack:
    1mg
    Price:
    $333
    Qty:
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  6. Gastrin I (human) (HB3575)

    Description:

    Selective CCK2 agonist. Endogenous peptide.

    Gastrin I (human)
    Pack:
    250μg
    Price:
    $99
    Qty:
    Pack:
    1mg
    Price:
    $265
    Qty:
    Supporting Docs Add to Favorites

  7. Ghrelin (rat) (HB2942)

    Description:

    Endogenous hormone. Ghrelin receptor agonist.

    Ghrelin (rat)
    Pack:
    1mg
    Price:
    $341
    Qty:
    Supporting Docs Add to Favorites

  8. GLP-1 (9-36) amide (HB3050)

    Description:

    Major metabolite of GLP-1 (7-36)

    Pack:
    1mg
    Price:
    $275
    Qty:
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  9. IRL-1620 (HB3411)

    Description:

    Highly selective ETB agonist

    IRL-1620
    Pack:
    500μg
    Price:
    $153
    Qty:
    Supporting Docs Add to Favorites

  10. LIH383 (HB9242)

    Description:

    Potent and selective ACKR3 (CXCR7) agonist. Potentiates opioid peptide activity.

    Pack:
    1mg
    Price:
    $172
    Qty:
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  1. Histone H3