Caged compounds

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Caged compounds are biomolecules whose activity can be modulated and controlled by light. The biomolecule is temporarily inactivated by being bound to a photolabile chemical group (a 'cage'). The application of light (visible or infra-red) removes this cage and enables the biologically active molecule to be released (photoreleased). These light-sensitive probes offer an enhanced way of controlling the timing and location of administration of these compounds and subsequent activation or inhibition of their biological target. Researchers can save up to 50% on caged compounds from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 45

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  1. A83-01 (HB3218)

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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    25mg
    Price:
    $297
    Qty:
  2. AG 490 (HB1424)

    Description:

    Selective EGF receptor tyrosine kinase inhibitor

    Purity:

    >99%

    Pack:
    50mg
    Price:
    $473
    Qty:
  3. AM 404 (HB1174)

    Description:

    Selective, competitive carrier-mediated anandamide transport inhibitor

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $64
    Qty:
    Pack:
    50mg
    Price:
    $255
    Qty:
  4. Description:

    Serotonin/norepinephrine reuptake inhibitor (SNRI)

    Purity:

    >98%

    Pack:
    1g
    Price:
    $127
    Qty:
  5. Pack:
    10mg
    Price:
    $157
    Qty:
    Pack:
    50mg
    Price:
    $568
    Qty:
  6. Description:

    Irreversible tryptophan hydroxylase inhibitor. Depletes 5-HT.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $58
    Qty:
  7. Pack:
    10mg
    Price:
    $66
    Qty:
    Pack:
    50mg
    Price:
    $199
    Qty:
  8. Cyclopamine (HB2965)

    Description:

    Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $196
    Qty:
    Pack:
    5mg
    Price:
    $746
    Qty:
  9. Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $827
    Qty:
  10. Pack:
    5mg
    Price:
    $78
    Qty:
    Pack:
    25mg
    Price:
    $311
    Qty:
    Pack:
    10mg
    Price:
    $74
    Qty:
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