Antagonists & inhibitors

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An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 16

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  1. A83-01 (HB3218)

    2  Reviews
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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    25mg
    Price:
    $297
    Qty:
  2. Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $827
    Qty:
  3. Description:

    TGF-β signaling inhibitor

    Purity:

    >95%

    Pack:
    5mg
    Price:
    $502
    Qty:
  4. Pack:
    10mg
    Price:
    $208
    Qty:
  5. Pack:
    10mg
    Price:
    $81
    Qty:
    Pack:
    50mg
    Price:
    $382
    Qty:
  6. Description:

    Potent, selective ROCK inhibitor

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $257
    Qty:
  7. GSK 429286 (HB2290)

    Description:

    Selective ROCK inhibitor

    Purity:

    >97%

    Pack:
    10mg
    Price:
    $270
    Qty:
  8. Description:

    Selective, reversible, cell-permeable ROCK inhibitor

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $230
    Qty:
  9. Description:

    Tyrosine kinase inhibitor that targets BCR‑ABL, c‑KIT, and PDGFR kinases

    Purity:

    >98%

    Pack:
    100mg
    Price:
    $86
    Qty:
  10. ITD 1 (HB3446)

    Description:

    Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $213
    Qty:
    Pack:
    50mg
    Price:
    $824
    Qty:
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