Antagonists & inhibitors

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An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

9 Items

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  1. Description:

    Phytohormone and endogenous lanthionine synthetase C-like 2 (LANCL2) ligand

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $139
    Qty:
    Pack:
    50mg
    Price:
    $608
    Qty:
  2. Azidothymidine (HB4602)

    Description:

    Selective reverse transcriptase inhibitor with anti-HIV activity. Decreases CRISPR-mediated homology directed repair (HDR) and enhances gene knockout efficiency.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $47
    Qty:
    Pack:
    250mg
    Price:
    $188
    Qty:
  3. 1  Review
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    Description:

    Broad-spectrum antibiotic. Used in inducible Tet-on/ Tet-off gene expression systems for gene editing.

    Purity:

    >95%

    Pack:
    1g
    Price:
    $32
    Qty:
    Pack:
    5g
    Price:
    $66
    Qty:
    Pack:
    10g
    Price:
    $114
    Qty:
    Pack:
    25g
    Price:
    $215
    Qty:
  4. 4  Reviews
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    Description:

    Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $102
    Qty:
    Pack:
    10mg
    Price:
    $182
    Qty:
    Pack:
    25mg
    Price:
    $374
    Qty:
    Pack:
    50mg
    Price:
    $662
    Qty:
  5. Description:

    Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $47
    Qty:
    Pack:
    50mg
    Price:
    $183
    Qty:
  6. 13  Reviews
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    Description:

    Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $69
    Qty:
    Pack:
    50mg
    Price:
    $239
    Qty:
  7. Nocodazole (HB3999)

    Description:

    Mitosis inhibitor, widely used as a cell cycle synchronizing agent. Enhances HDR efficiency and increases Cas9-mediated gene editing frequencies.

    Purity:

    >98%

    Pack:
    50mg
    Price:
    $389
    Qty:
  8. Rapamycin (HB2779)

    1  Review
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    Description:

    mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $140
    Qty:
    Pack:
    5mg
    Price:
    $237
    Qty:
  9. RS-1 (HB5647)

    Description:

    hRAD51 stimulator. Enhances CRISPR genome editing efficiency.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $63
    Qty:
    Pack:
    50mg
    Price:
    $270
    Qty: