Antagonists & inhibitors

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An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 212

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  1. 2-APB (HB1208)

    1  Review
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    Description:

    IP3 receptor and store-operated channels (SOC) channel antagonist

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $58
    Qty:
    Pack:
    50mg
    Price:
    $191
    Qty:
  2. Pack:
    1mg
    Price:
    $42
    Qty:
    Pack:
    5mg
    Price:
    $72
    Qty:
    Pack:
    10mg
    Price:
    $132
    Qty:
  3. Pack:
    25mg
    Price:
    $359
    Qty:
  4. A83-01 (HB3218)

    2  Reviews
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    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    25mg
    Price:
    $297
    Qty:
  5. 17-AAG (HB3599)

    Description:

    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $133
    Qty:
  6. (-)-Ageloxime D (HB3688)

    Description:

    Anticancer compound. Shows cytotoxic activity.

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $177
    Qty:
  7. Altersolanol A (HB3756)

    Description:

    Cytotoxin anthraquinone with various many actions

    Purity:

    >97%

    Pack:
    1mg
    Price:
    $174
    Qty:
  8. Anisomycin (HB2239)

    Description:

    Protein synthesis inhibitor. Potent JNK / p38 MAPK activator.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $72
    Qty:
    Pack:
    50mg
    Price:
    $279
    Qty:
    Pack:
    100mg
    Price:
    $491
    Qty:
  9. Aranorosin (HB3768)

    Description:

    Antibiotic with antibacterial, anticancer and antifungal activity

    Purity:

    >95%

    Pack:
    1mg
    Price:
    $202
    Qty:
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