Antagonists & inhibitors

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An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

2 Items

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  1. Anisomycin (HB2239)

    Description:

    Protein synthesis inhibitor. Potent JNK / p38 MAPK activator.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $72
    Qty:
    Pack:
    50mg
    Price:
    $279
    Qty:
    Pack:
    100mg
    Price:
    $491
    Qty:
  2. SP600125 (HB2234)

    Description:

    Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $74
    Qty:
    Pack:
    50mg
    Price:
    $310
    Qty: